OUR UNIT FOCUSES ON THE DEVELOPMENT AND APPLICATION OF NEW NANOMEDICINES AND PROBES FOR THE DIAGNOSIS, PROGNOSIS, AND TREATMENT OF VARIOUS DISEASES, INCLUDING CANCER, CELLULAR SENESCENCE AND AGING, INFLAMMATION, AND OTHER PATHOLOGIES.
Our research lines include:
- Design of nanomaterials with “molecular gates” for controlled drug release or biomolecule detection. This enables targeted action while minimizing undesired side effects.
- Development of lipid nanoparticles for gene therapy in rare diseases, immunotherapy, etc.
- Development of advanced systems incorporating interparticle or cell communication through chemical signals, enabling cooperative behaviors or autonomous movement. These “nanorobots” represent a promising frontier in nanomedicine for highly precise therapeutic applications.
- Development of molecular probes for detecting molecules or biomarkers of interest both in vitro and in vivo using colorimetric or fluorometric methods.
PRESENTATION
GET TO KNOW US BETTER
RESEARCH STAFF
THE PEOPLE WHO MAKE IT ALL POSSIBLE
Ramón Martínez Mañez
Vicente Candela Noguera
PUBLICATIONS
OUR SCIENTIFIC CONTRIBUTIONS
Glucose-Fueled Gated Nanomotors: Enhancing In Vivo Anticancer Efficacy via Deep Drug Penetration into Tumors.
ACS Nano 2025 Jun, DOI: 10.1021/acsnano.5c03799, Vol. 19, pag. 20932-20955
Targeting the senescent surfaceome through DPP4 antibody-functionalized nanoparticles. An application to cancer therapy.
BIOMATERIALS , DOI: 10.1016/j.biomaterials.2025.123461, Vol. 324, pag. 123461-123461
ß-Galactosidase-Triggered Photodynamic Elimination of Senescent Cells with a Boron Dipyrromethene-Based Photosensitizer.
Advanced Science 2024 Aug, DOI: 10.1002/advs.202401012, Vol. 11, pag.
