Joint Unit UPV-CIPF of Nanomedicine

The work of our unit is mainly based on the development and application of new nanomedicines and probes for diagnosis, prognosis, and therapy in various diseases. Our lines of research include:

-Development of nanomaterials with “molecular gates” for the detection of biomolecules and/or for the controlled release of drugs: Our objective is to develop nanosystems based on mesoporous silica nanoparticles, equipped with molecular gates that can retain a cargo within their pore system and deliver it by applying a specific stimulus (redox changes, pH changes, enzymes, light, magnetic fields, etc.). The development of these nanosystems allows the achievement of a controlled release of the cargo in the presence of the substance of interest or the controlled drug delivery in the diseased tissue, thus reducing unwanted side effects. Another of the lines of our research in the field of controlled cargo release includes the development of nanoparticles capable of communicating with each other or with cells through the exchange of chemical messengers, capable of cooperative work (nanorobots), or with autonomous movement capacity.

-Development of molecular probes: Another of the group’s lines of research is based on the development of chemical molecular probes for the detection of molecules or biomarkers of interest both in vitro and in vivo using colorimetric or fluorometric methods.