PRÓXIMOS EVENTOS
COMPARTIENDO IDEAS Y RESULTADOS DE INVESTIGACIÓN
PRÓXIMOS EVENTOS
COMPARTIENDO IDEAS Y RESULTADOS DE INVESTIGACIÓN
NUESTROS PRÓXIMOS EVENTOS
EVENTOS
Trabajamos para ser una referencia en el conocimiento, la difusión y la formación científica en Valencia, realizando regularmente eventos públicos y fortaleciendo las conexiones con entidades educativas y cívicas locales. Ofrecemos un calendario de eventos específicos para el público en general y para la comunidad científica.
este
mes
march 2024
14mar12:3013:30FBR: Luís Serrano
Event Details
Engineering a human lung bacteria for therapy Speaker: Luís Serrano Institution: Design of Biological Systems Lab. Centro de Regulación Genómica (CRG) Barcelona, Spain. Place: Jerónimo Forteza conference room, CIPF Abstract:
Event Details
Engineering a human lung bacteria for therapy
Speaker: Luís Serrano
Institution: Design of Biological Systems Lab. Centro de Regulación Genómica (CRG) Barcelona, Spain.
Place: Jerónimo Forteza conference room, CIPF
Abstract: Engineering bacteria to locally deliver therapeutic agents or to present antigens for vaccination is an emerging area of research with great clinical potential. Compared to drugs, nanoparticles and phages, bacteria provide several advantages when used as a vehicle to delivery therapies: i) they contain all the necessary biological machinery to synthesise complex therapeutics; ii) complex regulatory circuits that sense and respond specifically to diseased tissue can be integrated; iii) DNA integration into the host genome is improbable; iv) proliferation can be effectively controlled using antibiotics as a contingency strategy; and v) growth can be controlled by integrating suicidal circuits or auxotrophic dependence modules.
In our group, for many years we have analysed in the systems biology of the genome-reduced bacterium, MPN , a bacterium that causes mild pneumonia in humans. MPN offers an elegant approach to tackle lung diseases because it can be grown in a defined medium, it does not have a cell wall, it directly releases any secreted biomolecule into the medium, it does not recombine, and it has a unique genetic code that prevent genes from being passed onto other bacteria. We have already engineered this bacterium so that it is non-pathogenic and so that it does not cause an inflammatory response in mouse lungs. Within this bacterial chassis, we have also integrated genes encoding enzymes that are capable of dissolving bacterial biofilms caused by Gram-positive and – negative bacterial as well as and proteins that have bactericidal activity. This engineered bacterium can survive more than 4 days in the murine lung, causes no lesions, and induces a reduced inflammatory response when compared to its wildtype counterpart. We have shown that this chassis can be used to treat infectious bacterial diseases in mouse lungs, including those caused by P.aeruginosa.
Here I will present how the project started, where are we know and our future plans to use it for different lung diseases
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+01:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
próximo
mes
april 2024
11apr12:3013:30FBR: Josep Forment and Paola Marco-Casanova
Event Details
Title Speaker: Josep Forment and Paola Marco-Casanova Institution: Bioscience Department Director & Associate Director at AstraZeneca Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR: With
Event Details
Title
Speaker: Josep Forment and Paola Marco-Casanova
Institution: Bioscience Department Director & Associate Director at AstraZeneca
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
18apr12:3013:30FBR: Dr. Frank Westermann
Event Details
Title Speaker: Dr. Frank Westermann Institution: Neuroblastoma Research Group, Head Division, Hopp-Children’s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany. Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR:
Event Details
Title
Speaker: Dr. Frank Westermann
Institution: Neuroblastoma Research Group, Head Division, Hopp-Children’s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
25apr12:0013:00SEMINAR: Edna Ripollés / Jesús Alejandro Alzate
Event Details
12:00 – 12:30 Edna Ripollés Title Abstract 12:30 – 13:00 Jesús Alejandro Alzate Title Abstract
Event Details
12:00 – 12:30 Edna Ripollés
Title
Abstract
12:30 – 13:00 Jesús Alejandro Alzate
Title
Abstract
Time
(Thursday) 12:00 - 13:00(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
más
eventos
may 2024
16may12:0013:00SEMINAR: Marina fuentes Agudo / Daniel Tena González
Event Details
12:00 – 12:30 Marina fuentes Agudo Title Abstract 12:30 – 13:00 Daniel Tena González Inhibition of NLRP3 inflammasome in models of retinal degenerations Abstract
Event Details
12:00 – 12:30 Marina fuentes Agudo
Title
Abstract
12:30 – 13:00 Daniel Tena González
Inhibition of NLRP3 inflammasome in models of retinal degenerations
Abstract
Time
(Thursday) 12:00 - 13:00(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
june 2024
13jun12:3013:30FBR: Carlos Guillén
Event Details
Title Speaker: Carlos Guillén Institution: Diabetes & Obesity Lab, Universidad Complutense de Madrid, Madrid, Spain Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR: With support
Event Details
Title
Speaker: Carlos Guillén
Institution: Diabetes & Obesity Lab, Universidad Complutense de Madrid, Madrid, Spain
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
20jun12:0013:00SEMINAR: Mª del Mar Sánchez / Mª Ángeles Juanes
Event Details
12:00 – 12:30 Mª del Mar Sánchez Martín Abstract 12:30 – 13:00 Mª Ángeles Juanes Title Abstract
Event Details
12:00 – 12:30 Mª del Mar Sánchez Martín
Abstract
12:30 – 13:00 Mª Ángeles Juanes
Title
Abstract
Time
(Thursday) 12:00 - 13:00(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
july 2024
04jul12:3013:30FBR: Maria Mittelbrunn
Event Details
Title Speaker: Maria Mittelbrunn Institution: Inmunometabolism & Inflammation Lab, Centro de Biología Molecular Severo Ochoa, Madrid, Spain Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR:
Event Details
Title
Speaker: Maria Mittelbrunn
Institution: Inmunometabolism & Inflammation Lab, Centro de Biología Molecular Severo Ochoa, Madrid, Spain
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
october 2024
17oct12:3013:30FBR: Ivan Dikic Goethe
Event Details
Title Speaker: Ivan Dikic Goethe Institution: Molecular Signaling Lab, Goethe University Frankfurt, Frankfurt, Germany Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR: With support from
Event Details
Title
Speaker: Ivan Dikic Goethe
Institution: Molecular Signaling Lab, Goethe University Frankfurt, Frankfurt, Germany
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+02:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain
november 2024
14nov12:3013:30FBR: Lea-Laetitia Pontani
Event Details
Title Speaker: Lea-Laetitia Pontani Institution: Laboratoire Jean Perrin, Sorbonne Université, Paris, France Place: Jerónimo Forteza conference room, CIPF Abstract: PATROCINADO POR: With support from the Generalitat
Event Details
Title
Speaker: Lea-Laetitia Pontani
Institution: Laboratoire Jean Perrin, Sorbonne Université, Paris, France
Place: Jerónimo Forteza conference room, CIPF
Abstract:
PATROCINADO POR:
With support from the Generalitat Valenciana, AMPER-02/2023 and CIAORG/2022/035
Time
(Thursday) 12:30 - 13:30(GMT+01:00)
Location
Centro de Investigación Príncipe Felipe
Eduardo Primo Yúfera, 3 Valencia Spain